This is very possible because from the start Real Madrid and Manchester City were quite the favorites to win the UCL title this season, but unfortunately the meeting between the two teams happened too quickly.
Playing home or away may have a slight influence but it is not that significant and I think everything will be quite fair for both teams.
Yeah actually we don't expect this match in the quarter final because this is more appropriate in the final but there's nothing they can do and can't be avoided both teams must be prepared to get rid of each other. I didn't favorite one of them because both teams have the same opportunity but luck can help one of them, the question is who will be more fortunate in this fight? unpredictable, we have to wait for the match until the last minute. For the first leg match, of course the home team is more favored this means they have to use it as best they can.
This depends on how their performance will be, because it could be that one of them is unlucky by showing a game that is not like usual which will result in them finally having to admit defeat to their opponent, this applies to Real Madrid and Manchester City. It's a shame that their meeting happened so quickly, but we can't do anything about it because the lottery results say they have to meet in this round, even though most of us didn't expect this to happen now.
You are right, luck could be the difference in a tight match like this. Both clubs have beaten and eliminated each other before, in other words they have a record of experience in eliminating each other. With facts like that, of course it will be difficult for us to predict, even though the bookies actually give Manchester City a bigger chance of getting rid of Real Madrid. But all of that will be answered when they have finished 2 very decisive matches, and we have to watch it to see who will advance to the next round.