Quote from: myfy on Today at 08:32:57 AM

valid = ecdsa.verify((int(r,16),int(s,16)),bytes.fromhex(txid),Qa,curve=curve.secp256k1,hashfunc=sha256)
print(valid)

The "digest" that is used in signing and subsequently for verifying is not the txid, it is double SHA256 hash of a special serialization of the transaction that depends on the type of the output that was being spent.
For example since in this case the output that is being spent is a P2WPKH those steps are explained here: https://github.com/bitcoin/bips/blob/master/bip-0143.mediawiki