If it was the Real Madrid we know about, no one everly dares to bet against them in any condition. But the Real Madrid of today, I am not so confident that they will be able to win Slot boys. However it does not mean that they will outrightly lose. If I will advise anyone to bet on the game, they should just wait till few days or hours to the match. Many players could be injured in this international break and they will be unavailable for that great match. Let's not rush into it.
For some teams, international break make them, for some, it mares them.
Yes normally betting against Real Madrid would not be considered. They were always strong team. But now I am also not confident just like you that they will win against Slot boys. Their current performance has raised some doubts. That does not mean they will definitely lose though. Real Madrid still has chance. If you are thinking of betting wait until just before match. International break can bring injuries that affect team lineups. Some teams do well after break while others struggle. Let's wait and see what happens. It is better to be safe than sorry when making betting decisions.
There are still 2 weeks left and anything can happen in a short time as you said. Injured players are always a bad choice for a team and this is not only true for Madrid but the opposing team can be worse when they lose injured players.
From the hopes of Madrid fans when facing Liverpool, only a draw is the best result if they can't beat Liverpool. It may seem bad for one of Madrid big teams to end in a draw. But that result would be better than losing.
Most likely if Liverpool loses important players injured, maybe taking a gamble on a draw is the best choice.