I don't think PSV will be able to win Juventus. Even though Juventus form this season has been not been so good, they have dropped points in matches that they should have won, I think their overall squad depth and experience in European competitions give them an edge over PSV. I doubt PSV have the technical ability or experience needed to eliminate Juventus.
Defeating Juventus will not be an easy job for PSV because if we compare the depth of the squad of both teams, of course Juventus is superior and in terms of their experience in this competition there is no doubt, but not easy does not mean impossible, if PSV uses the right strategy in the first leg when visiting Juventus' headquarters then in the 2nd leg PSV will be more confident.
Let's see what both teams will do in this crucial match, if PSV can really destroy Juventus I think Motta's career will be threatened.
There will be no easy match for the Champions League play-offs. Those who underestimate their opponents may get a surprise. PSV and Juventus are no exception. Both are good teams, it's just that Juventus currently plays a more defensive style of play. Even in many matches, they have to be satisfied with a draw. It all depends on how PSV will strategize in the next match to gain an advantage over Juventus' defensive play. I think a draw might happen in one of the matches.