I don't think PSV will be able to win Juventus. Even though Juventus form this season has been not been so good, they have dropped points in matches that they should have won, I think their overall squad depth and experience in European competitions give them an edge over PSV. I doubt PSV have the technical ability or experience needed to eliminate Juventus.
Defeating Juventus will not be an easy job for PSV because if we compare the depth of the squad of both teams, of course Juventus is superior and in terms of their experience in this competition there is no doubt, but not easy does not mean impossible, if PSV uses the right strategy in the first leg when visiting Juventus' headquarters then in the 2nd leg PSV will be more confident.
Let's see what both teams will do in this crucial match, if PSV can really destroy Juventus I think Motta's career will be threatened.
If we talk about experience for me both teams have the same experience in the UCL League, it can be said that both Juventus and PSV are European giants that are currently sleeping. Because both teams are teams that are experienced in the UCL League, and have champion titles in this competition. PSV has won the UCL title once, while Juventus has two UCL League titles twice. Indeed, if we talk about history it will not change anything but mentally I think it will have a little effect.
Yes, if we talk about the squad, of course Juventus is better than PSV, especially in the first match Juventus acted as the host, of course this will be an extra strength to achieve victory by scoring a quick goal. Because if Juventus wins this will be a good capital to visit PSV in the second leg later. But what is clear is that the game of the two teams is very different so the prediction is that this match will be fierce and interesting. Personally, I want Juventus to qualify for the last 16.