I rarely bet, betting i don't think i would bet on Manchester United because they are difficult to predict and have played really badly in recent years, but Sevilla's history in the Europa League could make you think that Manchester United have a similar chance.
Although i don't think so.
That is a smart decision. Betting on United isn't a smart decision at the moment because that is a volatile team and we have no clue how they will look. Europa is a bit different because they are facing even harder teams here, at premier league sometimes they face very tough teams but usually they play teams they should be able to win against. This makes it very hard for them to have some trouble in these easy games and lose.
Lyon isn't one of those, Lyon is a team that is equal to United, not that commonly happening for United, they either play against better premier league teams or worse, not many premier league teams could be considered equal to United at the moment. So betting on this game would be even more risky, I won't bet either.