If it is the company that is taken the loan I don't think if there's anything wrong with that, because we are 100% sure that they will pay back the money in due time. Though sometimes a company can decide to take loan from bank or even from thier fellow companies, when they must have run out with cash/funds. However, is obvious that bitcoin is a very good asset in the future but anyone who can not afford to invest in bitcoin should not go for a loan. Because the market is decentralized Which means that no one have control over it, so if there's any dip or increase in the price there's nothing you can do than to panick.
Lenders in this era are also smart enough to see people or companies who want to lend their funds so that not all companies can do this if the lender knows that the company will soon go bankrupt. Because at this time all parties who often serve loans to other parties also have people who directly check them directly before the loan is given and this is done so as not to cause problems in the future. Moreover, some borrowers also do not know themselves that they are actually unable to pay if the sales of their company are not going well.