I tried it and had the same experience. Minera doesn't work very well for me at all, ever. Regardless of version and any tweaks and regardless of what miner software I activate within Minera, it's low rate and higher than 95% HW errors.
I did discover that an Atom 450 based netbook running cgminerdmaxl with USB hubs can easily handle 10 ASICs, if that helps you any. I ran that way for a week, to see how it would go.
A quad AMD Phenom with the same setup does just fine and can handle even more ASICs.
Is anyone mining SYS using Minera? I have been having a real hard time finding a pool that is compatible with the mining software (and doesn't screw you on the hashrate).
I found it has more to do with the pool. The blades really run well under minera. Just have to connect to the right pool. I tried MinderPools and the offical pool, the miners doesn't like either. The pool was under reporting the hash rate by 10-15%