You can overclock beyond BIOS limits using the new Catalyst 11.6 drivers without having to reflash. You can underclock memory to 300 using AMDOverdrivectrl. Not sure you gain much going below 300. There are also 3-5% gains with some of the changes to the phatk kernel. Do a search.
If you're going through the trouble of installing the latest drivers, setting up the APP SDK and compiling PyOpenCL to get your miner working why bother with a GUI when a 2 line shell script will do.